TENLIFENS-M ER 500

Teneligliptin 20mg & Metformin Hydrochloride (ER) 500mg Tablets- The tablet is a combination medication used to manage Type 2 diabetes by increasing insulin release and reducing glucose production. It provides potent, synergistic, and sustained glycemic control. The tablets are reliable and safe for hypoglycemia and weight neutrality.

Unlike sulfonylureas, Teneligliptin enhances insulin in a glucose-dependent manner. The extended-release version of Metformin minimizes common gastrointestinal side effects and improves patients’ convenience for long-term treatment. It is often considered a cost-effective option in many regions, thereby balancing premium quality with affordability. The combination requires only one dose daily as compared to taking separate medications.

Medfence Labs develops and sells Teneligliptin & Metformin Hydrochloride (ER) Tablets under the brand name Tenlifen-M ER 500.  The company has a diverse product portfolio in key therapeutic areas, including dermatology, antibiotics, nutritional supplements, and pediatric ranges. Their products are ISO and WHO-GMP certified. They also provide PCD pharma franchise opportunities with monopoly rights and promotional support.

Mechanism of Teneligliptin & Metformin Hydrochloride (ER) Tablets 

Teneligliption blocks the Dipeptidyl peptidase-4 (DPP-4) enzyme, which usually breaks down GLP-1 and GIP. These hormones help the pancreas release more insulin and reduce glucagon, but only when blood sugar is high. In this way, Teneligliptin helps control blood sugar safely and effectively.

Metformin mainly lowers sugar made by the liver, helps muscles use sugar better, and also reduces sugar absorption in the gut. The ER form releases slowly, which often reduces stomach side effects while keeping blood sugar under control.

Benefits of Teneligliptin & Metformin Hydrochloride (ER) Tablets 

The key benefits of these tablets include:

• Effective blood sugar control
• Lower risk of blood sugar control
• Minimal weight gain
• Convenient dosage
• Prevents long-term complications such as blindness and cardiovascular issues. 

Side Effects of Teneligliptin & Metformin Hydrochloride (ER) Tablets 

The combination is generally well-tolerated but has some potential side effects. Such reactions often recede as the body adjusts to the treatment. Consult a healthcare professional if any concern arises.

• Diarrhea
• Nausea
• Vomiting
• Abdominal pain
• Bloating
• Constipation
• Dizziness
• Sweating’
• Shaking
• Headaches
• Sore throat
• Nasal congestion
• Potential weight gain
• Vitamin B12 deficiency
• Fatigue
• Numbness

Precautions for Teneligliptin & Metformin Hydrochloride (ER) Tablets 

To ensure safe and effective use, this medicine should be taken with proper care and medical advice. Individual health conditions, lifestyle factors, and treatment duration can influence how the body responds. By keeping the following precautions in mind, you can reduce the unwanted effects.

• Consume this medication with meals to reduce stomach upset. Swallow the tablet as a whole; do not crush or chew.
• Do not consume alcohol while taking this medication, as it increases the risk of lactic acidosis and low blood sugar.
• Seek immediate medical attention if you experience fatigue, muscle pain, breathing difficulties and severe drowsiness.
• Take caution as the drug can stay too long in the body if the kidneys or liver are damaged, so it is not recommended for people who have kidney/liver disease.
• Check blood sugar levels regularly if you notice symptoms such as dizziness, tremor, or sweating.
• Inform your doctor in advance if you are undergoing surgery oran  X-ray/scanning procedure using contrast agents, as these could affect the working of the medication in your body.
• The tablets are not recommended for pregnant or breastfeeding women.
• Inform your doctor if you are taking diuretics, corticosteroids, phenothiazines, oral contraceptives, or thyroid medication, as they may interact with the medication.

Frequently Asked Questions

Q1- Why do I see Teneligliptin & Metformin Hydrochloride Tablets shells in my stool?

A- The tablets are designed to release the medication gradually after 12-24 hours, so it is a harmless phenomenon.

Q2- Who is an ideal candidate for Teneligliptin & Metformin Hydrochloride Tablets?

A- Adults with Type 2 diabetes, patients needing post-meal control, and weight-conscious patients are ideal candidates for these tablets.

Q3- If someone has kidney disease, then should he not take Teneligliptin & Metformin Hydrochloride Tablets?  

A- It depends on the stage of their kidney disease. They require strict medical supervision for the exact dosage 

Q4- Are the Teneligliptin & Metformin Hydrochloride Tablets safe for elderly patients?

A- Take caution with elderly patients, make sure that they do not have reduced kidney function.

Q5-How is Teneligliptin & Metformin Hydrochloride Tablets’ extended release version different from immediate release tablets?

A- The tablets differ in their rate of drug absorption, dosing frequency, and gastrointestinal tolerability.

Q6- What to do to improve Vitamin B12 deficiency caused by Teneligliptin & Metformin Hydrochloride Tablets?

A- Take Vitamin B12 supplement in combination with calcium under a doctor’s supervision for continuing these tablets.

Q7- How long does Teneligliptin & Metformin Hydrochloride Tablets take to see blood glucose improvement?

A- The tablets will take around 12 weeks to see improvement in blood glucose.