GLIMIFENS-M1

Glimepiride 1mg and Metformin 500mg Bilayer Tablets- The combination tablets are widely used to manage type 2 diabetes mellitus effectively. It is an antidiabetic formulation, composed of two medications, namely Glimepiride and Metformin. This bilayer formulation combines two complementary agents that work through different mechanisms to provide superior glycemic control. It helps regulate blood sugar levels while reducing insulin resistance, making it suitable for patients who do not achieve adequate control with single therapy.

The tablet is especially beneficial for long-term diabetes management, as it targets both insulin secretion and glucose production. Glimepiride stimulates insulin release from pancreatic beta cells, while Metformin decreases hepatic glucose output and improves peripheral glucose uptake. Medfence Labs is a leading and trusted manufacturer of Glimepiride 1mg and Metformin 500mg Bilayer Tablets, under the brand name GLIMIFENS-M1. 

Working Mechanism of Glimepiride 1mg and Metformin 500mg Bilayer Tablets

This combination works by offering active results in controlling the blood glucose level. The working mechanisms of the combined active action are explained as follows: 

• Glimepiride Action: Enhances insulin secretion from the pancreas to lower blood glucose.
• Metformin Action: Reduces glucose production in the liver and improves insulin sensitivity.

Together, they help maintain stable blood glucose levels, reduce post-meal sugar spikes, and support overall metabolic balance when combined with proper diet and exercise

Benefits and Uses of Glimepiride and Metformin Tablets

This triple-action approach of the combination medication helps manage. A List of other benefits is mentioned as follows:

• Type 2 Diabetes Management: Helps control blood sugar in adults with type 2 diabetes.
• Dual Glycemic Control: Targets insulin deficiency and insulin resistance together.
• Reduced Sugar Spikes: Controls post-meal hyperglycemia effectively.
• Long-Term Metabolic Support: Supports better glycemic stability with continued use

Side Effects of Glimepiride 1mg and Metformin 500mg Bilayer Tablets

Most of the side effects disappear as the body adjusts to the dose. A List of them has been mentioned as follows. Consult your healthcare professional if they persist and cause discomfort. 

• Nausea
• Diarrhea
• Headache
• Upper respiratory tract infection
• Dizziness
• Flatulence

Safety Measures and Precautions While Using Glimepiride and Metformin Tablets

Disclose all your past and current health issues to your doctor. A list of safety precautions has been mentioned to avoid any adverse reactions.

• Only use this medication as prescribed by your healthcare professionals and take it as per the recommendation.
• Avoid taking it on your own if you’re pregnant or breastfeeding. Consult your doctor beforetaking this tablet in these health conditions.
• Maintain a proper diet, exercise regularly, eat a healthy diet, and take your other diabetes medications.
• Take these medications with food to avoid upsetting the stomach.
• Monitor the blood glucose level frequently while taking these medications. 

How To Store Glimepiride and Metformin Bilayer Tablets

Follow the instructions mentioned below as follows:

• Store in a cool, dry place at (25-28°C).
• Keep this tablet away from direct sunlight. 
• Keep out of reach of children.
• Avoid the use of the tablet after the expiry date.

Frequently Asked Questions (FAQs)

Q1. What is Glimepiride 1mg and Metformin 500mg used for?
It helps control blood sugar levels in adults with type 2 diabetes when diet and exercise are insufficient.

Q2. How does this combination work in diabetes management?
Glimepiride increases insulin release, while Metformin reduces glucose production and improves insulin sensitivity.

Q3. Who should take Glimepiride and Metformin tablets?
It is prescribed for adults with type 2 diabetes under medical supervision.

Q4. Can this medicine be taken with food?
Yes, it is usually taken with meals to reduce stomach discomfort and improve tolerance.

Q5. How often should these tablets be taken?
Dosage and frequency depend on medical advice, usually once or twice daily.

Q6. Does this medicine cause low blood sugar?
Glimepiride may cause hypoglycemia if meals are skipped or the dosage is incorrect.

Q7. Is this tablet suitable for long-term use?
Yes, when taken as prescribed, it supports long-term blood sugar control.

Q8. Can elderly patients use this medication?
Elderly patients may use it with dose adjustments and regular blood glucose monitoring.