VOGIFEN-0.2 DT

Voglibose 0.2mg and Metformin Hydrochloride 500mg Tablets- The two ingredient fixed dose medication is used in the treatment of Type 2 Diabetes Mellitus. The medicine provides a synergistic, dual action approach that simultaneously addresses both fasting and after-meal blood glucose levels, particularly in diets high in carbohydrates. 

The combination medication rarely causes low blood sugar, which makes it safer for long-term use. Metformin has weight-reducing effects, while Voglibose has a neutral or positive effect on weight. This makes the combination ideal for overweight or obese diabetic patients. It is favoured in clinical practice due to its high efficacy in lowering HbA1c and improved gastrointestinal safety.

Medfence Labs manufactures and supplies Voglibose and Metformin under the brand name Vogifen-0.2 DT.  It is a Panchkula-based company established in 2017. The company provides a wide range of medicines, including tablets, capsules, syrups, and injectables. It also provides monopoly-based PCD pharma franchises across India.

Mechanism of Voglibose and Metformin Tablets 

Voglibose is a reversible inhibitor of membrane-bound intestinal alpha-glucosidase enzymes, specifically sucrase, maltase and isomaltase. It delays the digestion and absorption of dietary carbohydrates in the small intestine, which further helps in reducing postprandial blood glucose spikes. It can also increase the release of GLP-1 that helps manage glucose.

Metformin works by reducing liver glucose production. It improves insulin sensitivity in peripheral tissues, which enhances glucose uptake. It may also reduce glucose absorption from the intestine.

Benefits of Voglibose and Metformin Tablets 

Mentioned below are the key benefits of the tablets.

• Reduces Postprandial Glucose 
• Lowers HbA1c levels
• Improves Insulin Sensitivity 
• Lower blood risk
• Weight management 
• Prevents complications 
• Better compliance 

Side Effects of Voglibose and Metformin Tablets 

Like most medications, this combination tablet may cause certain unwanted effects. These effects are mild and temporary. However, seek medical advice from your doctor if any of the symptoms persist. 

• Diarrhea
• Abdominal Pain
• Bloating 
• Nausea 
• Vomiting
• Flatulence
• Constipation
• Low blood sugar
• Reduced appetite
• Metallic taste
• Dizziness
• Headache
• Tremors

Consult your doctor as soon as possible if you notice serious side effects.

Precautions for Voglibose and Metformin Tablets 

To ensure safe and effective use, this medicine should be taken with appropriate care and medical advice. Be mindful of the following precautions as they will help in reducing the unwanted effects.

• Take medication with meals to reduce stomach upset and effectively control post-meal sugar spikes.
• The tablets can cause low blood sugar if doses are missed or combined with other anti-diabetic drugs. Carry juice or candy.
• Due to metformin, you may feel dizzy, experience rapid breathing, and intense muscle pain, especially if you have kidney or liver issues.
• Maintain a consistent diet and exercise routine.
• Do not drink excessive alcohol, as it can increase the risk of both low blood sugar and lactic acidosis.
• Consult a doctor if you are pregnant, breastfeeding or have severe infections or surgeries, as the tablets may not be suitable.
• Take caution as dizziness from low blood sugar may affect your ability to drive.
• Regular blood tests to check kidney function and HbA1c levels.

Frequently Asked Questions

Q1- How are Voglibose and Metformin tablets different from Vildagliptin and Metformin tablets?

A- Voglibose and Metformin targets post meal sugar spikes, while Vildagliptin and Metformin enhance insulin secretion and reduce liver glucose production.

Q2- Why do Voglibose and Metformin tablets cause gas or stomach discomfort?

A- Take the medication with food to avoid stomach discomfort or gas.

Q3- Do Voglibose and Metformin tablets affect body weight?

A- Yes, the combination reduces the body weight in individuals with type 2 diabetes or those with obesity.

Q4- Can I take Voglibose and Metformin tablets if a meal is skipped?

A- It is generally not advised to take the tablets if the meal is skipped.

Q5- Are there any dietary instructions to follow while taking Voglibose and Metformin tablets?

A- Follow a rich fibre diet including whole-grains, vegetables and fruits with low glycemic index.

Q6- How long will Voglibose and Metformin tablets take to see improvement in post-meal blood sugar?

A- The tablets start improving the post-meal blood sugar within 1-2 hours of the first dose.

Q7- Can Voglibose and Metformin tablets interfere with the digestion of all nutrients?

A- They do not prevent the body from digesting fats, proteins, or most essential nutrients.